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Medications that can interfere with CYP2D6: Cell with estrogen receptors blocked by tamoxifen and helper proteins Larger Version Most doctors recommend taking tamoxifen at the same time each day. Your doctor may recommend no additional therapy or extended hormonal therapy with tamoxifen or an aromatase inhibitor depending on your risk of recurrence, your overall medical condition, and your preferences. You should use an effective non-hormonal type of birth control — such as condoms, a diaphragm along with spermicide, or a non-hormonal I.
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Skip the missed dose if it is almost time for your next scheduled dose. Together, you and your doctor can decide if CYP2D6 testing makes sense for your unique situation. You may also need to have a pregnancy test before you start taking tamoxifen, to make sure you are not pregnant.
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The shock of a diagnosis, the disruption of your life, getting through and beyond surgery and radiation, the strain of relationships at home and at work, financial stress, and less physical activity all may contribute to weight gain. I have ulcerative colitis and had been taking an over the counter pill Digestive Advantage for Colon Health that worked well. The risk is similar to taking estrogen hormone replacement therapy.
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The balance appears to favour the benefit of treatment, with an absolute reduction in breast cancer mortality of 2. There was a trend toward more endometrial cancers in the tamoxifen group over extended follow-up, with a total of 29 vs 20 in the placebo group; most of the endometrial cancers in the tamoxifen group occurred over the first 5 years, when patients were on active treatment. How did the researchers interpret the results?
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By RICHARD DOOLEY
The Daily News

Monday, September 02, 2002